Calan versus propranolol for migraines

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Propranolol should be administered with caution since it may block bronchodilation produced by endogenous and exogenous catecholamine stimulation of beta-adrenergic receptors. Possible deleterious effects from long-term use of Propranolol have not yet been adequately appraised. Propranolol from Inderal capsules is almost completely absorbed from the gastrointestinal tract. Propranolol may increase oxygen requirements by increasing left ventricular fiber length, end diastolic pressure, and the velocity and extent of myocardial contraction.

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