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Keep Olanzapine in the container it came in, tightly closed, and out of reach of children. If you are currently taking Zyprexa and have concerns about its safety, you should contact you doctor for additional information and a review of your case. High blood sugar. Zyprexa and some medicines may interact with each other and may not work as well, or cause possible serious side effects. Olanzapine must be taken regularly for a few weeks before its full effect is felt. Although side effects from Zyprexa are not common, they can occur. Symptoms of a Zyprexa overdose may include drowsiness, agitation, aggression, slurred speech, confusion, increased heart rate, jerky or uncontrolled muscle movements, trouble breathing, or fainting. If you have taken Zyprexa and developed accelerated weight gain, diabetes, or pancreatitis, you should contact you doctor for additional information and a review of your case. Avoid using cold medicine, pain medication, muscle relaxers and medicine for seizures that make you sleepy.