If taken on an empty stomach at least one hour before a meal. Esomeprazole works best if taken on an empty stomach at least one hour before meals, swallowed whole and shouldn't be crushed or chewed. When you buy Nexium from the merchants listed on our website, all orders are confidential. Our Nexium prices are the lowest available online and updated monthly. Nexium is available in a powdered intravenous formulation to be reconstituted for injection. Nexium is the newer formulation of the original Omeprazole product - both prescription drugs used to treat ulcers, gastroesophageal reflux disease, and other conditions caused by excess stomach acid. You will need to take Nexium, or you have ever had an allergic reaction, you will not be able to take Nexium. Our website, all orders are confidential. What should you watch for while taking Esomeprazole?