If you are or will be breast-feeding while you use Hydrochlorothiazide, check with your doctor. Hydrochlorothiazide may cause you to become sunburned more easily. Some of the side effects that may occur while taking Microzide include black, tarry stools blood in urine or stools cough or hoarseness fever or chills joint pain lower back or side pain painful or difficult urination. If you have diabetes you should carefully monitor your blood sugar may be enhanced if you are or will be breast-feeding while you use Hydrochlorothiazide.