Read about nexium: "Esomeprazole capsules should be applied one hour before meals and at the same time every day. Esomeprazole works best if taken on an empty stomach at least one hour before a meal. Esomeprazole is available with a doctor's prescription and is commonly called by its brand name, Nexium. You buy Nexium from the merchants listed on our website, all orders are confidential. If taken on an empty stomach at least one hour before a meal."