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Celexa is an astonishing antidepressant medication that affects neurotransmitters, the chemical transmitters within the brain. Celexa causes less drug interactions, you should always let your doctor know what other medications you are taking. Take Celexa together with a monoamine oxidase inhibitor. The treatment of depression, Celexa extends the length of time serotonin remains active in the brain. Although Celexa is noted for its reduced instances of drug interactions, which could make the antidepressant a good choice for medically compromised individuals such as the elderly or those with co morbid illness. The first choice for the treatment of depression. Ssri medications affect the levels of serotonin in the brain. Citalopram is primarily used to treat the symptoms of depression but can also be prescribed for social anxiety disorder, panic disorder or obsessive-compulsive disorder.