By stomach acid or infection. Nexium is usually taken once a day at least one hour before meals, swallowed whole and shouldn't be crushed or chewed. Esomeprazole prevents symptoms and damage to the gastrointestinal tract caused by stomach acid or infection. For nearly 9 out of 10 patients. Nexium decreases the amount of acid produced in the stomach. Taking Esomeprazole? Nexium is used to treat the symptoms of GERD and other conditions involving excessive stomach.
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