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The body called cyclo-oxygenase. Celecoxib is used to treat arthritis, pain, menstrual cramps, and colonic polyps. This medication should not be used if you have certain medical conditions. Celecoxib should only be used in pregnant women when the benefits outweigh the potential risk to the fetus. Before using this medication, tell your doctor or pharmacist your medical history, especially of blood flow problem in the brain. It as instructed by your doctor.